For The First Time, Scientists Create a 3D Map of Chromosomes’ Organization !

In collaboration with researchers from the Weizmann Institute in Israel, a team from the Institut de Génétique Humaine (CNRS) has, for the first time, revealed the detailed three-dimensional architecture of chromosomes: Giacomo Cavalli and his colleagues have achieved high-resolution mapping of the different contacts that exist within and between chromosomes. They performed this feat using a new very high-throughput technique improved by the Montpellier team. This major research work should shed new light on the impact of 3D chromosome organization on genome expression and on the onset of diseases such as cancer. It is published in the online version of the journal Cell of 19 January 2012. Continue reading

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